Homology
Introduction to protein homology
Understanding of the evolutionary history of organisms and specifically of particular proteins is accomplished through analysis of similarities and differences between organism proteomes. Knowledge derived from proteome comparisons of different species can be integral in understanding not only the function of a protein but also the relationships of proteins between species.
Homology is the study of protein similarities between species through inheritance from a common ancestor. A homologous protein is a protein, or variation of a protein, that is present in two different species that can be traced to origination in a common ancestor shared by both of the different species. Identification of proteins that are highly conserved in a variety of species can not only elucidate the evolutionary development of current species, but also assist in identification of organisms suitable for laboratory research for further study of specific protein function and disfunction.
Homology is the study of protein similarities between species through inheritance from a common ancestor. A homologous protein is a protein, or variation of a protein, that is present in two different species that can be traced to origination in a common ancestor shared by both of the different species. Identification of proteins that are highly conserved in a variety of species can not only elucidate the evolutionary development of current species, but also assist in identification of organisms suitable for laboratory research for further study of specific protein function and disfunction.
Homology and reference pages
Pendrin homologues
This web page was produced as an assignment for Genetics 564 at UW-Madison Spring 2014